Conjugated Linolenic Acids (CLnA) and Methyl Esters

Conjugated linolenic acids (CLnAs) contain 3 or 4 double bonds (which can be any combination of cis or trans) having predominantly 9,11,13- and 8,10,12-octadecatrienoic acid positional isomers. Research indicates that CLnAs posses strong antidiabetic, antiobesity, antiproliferative, and anticarcinogenic activities as well as a significant effect on lipid metabolism making them important biological lipids.1 These physiological functions make CLnAs potential candidates as therapeutic and diabetic agents, although more research is needed to verify previous findings.2


  1. P. Aruna et al. Health Benefits of Punicic Acid: A Review. Comprehensive Reviews in Food Science and Food Safety., Vol. 15 pp. 16-27, 2016
  2. I. Pereira et al. Pomegranate Seed Oil (Punica Granatum L.): A Source of Punicic Acid (Conjugated α-Linolenic Acid). Journal of Human Nutrition and Food Science., Vol. 2(1) pp. 1024, 2014

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Methyl alpha-eleostearate