D,L-threo-PPMP

CATALOG # 1720
Amount 100 mg
Price $250.00
Qty
 
D,L-threo-PPMP
  • Catalog #:1720
  • Scientific Name:D,L-threo-PPMP
  • Common Name:D,L-threo-l-Phenyl-2-hexadecanoylamino-3-morpholino-propanol·HCl
    Activity: glucosylceramide synthase inhibitor
  • Empirical Formula:C29H50N2O3HCl
  • CAS#149022-18-4
  • SDSView Material Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:511
  • Unit:100 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC; identity confirmed by MS
  • Solubility:alcohols, chloroform
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. B. Maurer et al. “Synergistic Cytotoxicity in Solid Tumor Cell Lines Between N-(4-Hydroxyphenyl)retinamide and Modulators of Ceramide Metabolism” Journal of the National Cancer Institute, Vol. 92(23) pp. 1897-1909, 2000
    2. A. Puri et al. “Human Erythrocyte Glycolipids Promote HIV-1 Envelope Glycoprotein-Mediated Fusion of CD4+Cells” Biochemical and Biophysical Research Communications, Vol. 242 pp. 219-225, 1998
    3. A. Couto et al. “Glycosphingolipids in Plasmodium falciparum: Presence of an active glucosylceramide synthase” European Journal of Biochemistry, Vol. 271 pp. 2204-2214, 2004
    4. D. Sillance et al. “Glucosylceramide modulates membrane traffic along the endocytic pathway” Journal of Lipid Research, Vol. 43 pp. 1837-1845, 2002