D-threo-PDMP

CATALOG # 1756
Amount 10 mg
Price $345.00
Qty
 
D-threo-PDMP
  • Catalog #:1756
  • Scientific Name:D-threo-PDMP
  • Common Name:D-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl;
    Activity: glucosylceramide synthase inhibitor
  • Empirical Formula:C23H38N203•HCl
  • CAS#109836-82-0
  • SDSView Material Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:427
  • Unit:10 mg
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC; identity confirmed by MS
  • Solubility:ethanol, methanol
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. R. Vunnam, N. Radin, “Analogs of ceramide that inhibit glucocerebroside synthetase in mouse brain” Chem Phys Lipids, Vol. 26(3) pp. 265-278, 1980
    2. N. Radin et al. “Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells” Journal of Cellular Physiology, Vol. 141(3) pp. 573-583, 1989
    3. N. Radin, et al., “Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth” Journal of Lipid Research, Vol. 36 pp. 611-621, 1995