L-MAPP

CATALOG # 1860
Amount 100 mg
Price $210.00
Qty
 
L-MAPP
  • Catalog #:1860
  • Scientific Name:L-MAPP
  • Common Name:L-erythro-2-Tetradecanoylamino-1-phenyl-1-propanol
    Activity: inactive as alkaline ceramidase inhibitor
  • Empirical Formula:C23H39NO2
  • CAS#143492-38-0
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:361
  • Unit:100 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC
  • Solubility:ethanol
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. A. Bielawska et al. “(1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase” The Journal of Biological Chemistry, vol. 271 pp. 12646-12654, 1996
    2. S. Payne et al. “Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts” Cellular Physiology, vol. 180 pp. 263-270, 1999
    3. C. Rodriguez-Lafrasse et al. “Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing” International Journal of Cancer, vol. 101 pp. 589-598, 2002
    4. N. Auge et al. “Oxidized LDL-Induced Smooth Muscle Cell Proliferation Involves the EGF Receptor/PI-3 Kinase/Akt and the Sphingolipid Signaling Pathways” Athersclerosis, Thrombosis, and Vascular Biology, vol. 22 pp. 1990-1995, 2002