N-omega-CD3-Octadecanoyl-D-erythro-dihydrosphingosine

CATALOG # 2202
Amount 1 mg
Price $325.00
Qty
 
N-omega-CD3-Octadecanoyl-D-erythro-dihydrosphingosine
  • Catalog #:2202
  • Scientific Name:N-omega-CD3-Octadecanoyl-D-erythro-dihydrosphingosine
  • Common Name:N-C18:0-CD3-D-erythro-Dihydroceramide; N-Stearoyl-CD3-D-erythro-sphinganine
  • Empirical Formula:C36H70D3NO3
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:571
  • Unit:1 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC, GC, HPLC, identity confirmed by MS
  • Solubility:hot ethanol, DMF, DMSO, chloroform/methanol 2:1
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. Magkos, F. and Mittendorfer, B., “Stable isotope-labeled tracers for the investigation of fatty acid and triglyceride metabolism in humans in vivo” Clin Lipidol. Vol. 4 pp. 215–230, 2009
    2. Byun, H. and Bittman, R. Selective deuterium labeling of the sphingoid backbone: facile syntheses of 3,4, 5-trideuterio-d-erythro-sphingosine and 3- deuterio-d-erythro-sphingomyelin” Chem Phys Lipids, Vol. 163(8) pp. 809-813, 2010
    3. Y. Mizutani, A. Kihara, and Y. Igarashi “Identifcation of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation” FEBS Letters, vol. 563 pp. 93-97, 2004
    4. J. Soriano et al. “Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1” Progress in Lipid Research, Vol. 44 pp. 345-356, 2005
    5. W. Zheng “Fenretinide increases dihydroceramide and dihydrosphingolipids due to inhibition of dihydroceramide desaturase” Georgia Institute of Technology, 2006
    6. J. Idkowiak-Baldys et al. “Dihydroceramide Desaturase Activity is Modulated by Oxidative Stress” Biochem. J., Vol. 427(2) pp. 265-274, 2010
    7. J. Stiban et al. “Dihydroceramide hinders ceramide channel formation: Implications on apoptosis” Apoptosis, Vol. 11(5) pp. 773-780, 2006