N-omega-CD3-Octadecanoyl monosialoganglioside GM3 (NH4+salt)

CATALOG # 2052
Amount 250 ug
Price $410.00
Qty
 
N-omega-CD3-Octadecanoyl monosialoganglioside GM3 (NH4+salt)
  • Catalog #:2052
  • Scientific Name:N-omega-CD3-Octadecanoyl monosialoganglioside GM3 (NH4+salt)
  • Common Name:N-CD3-Stearoyl-GM3
  • Empirical Formula:C59H105D3N2O21•NH3
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:1185+NH3
  • Unit:250 ug
  • Source:semisynthetic, bovine buttermilk
  • Purity:98+%
  • Analytical Methods:TLC, identity confirmed by MS
  • Solubility:chloroform/methanol/water, 2:1:0.1; forms micellar solution in water
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. J. Gu, C. Tifft and S. Soldin “Simultaneous quantification of GM1 and GM2 gangliosides by isotope dilution tandem mass spectrometry” Clinical Biochemistry, Vol. 41(6) pp. 413-417, 2008
    2. L. Svennerholm, et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980
    3. T. Kolter, R. Proia, K. Sandhoff “Combinatorial Ganglioside Biosynthesis” J. Biol. Chem., Vol. 277:29, pp. 25859-25862, 2002
    4. S. Birkle, G. Zeng, L. Gao, R. K. Yu, and J. Aubry “Role of tumor-associated gangliosides in cancer progression” Biochimie, Vol. 85 pp. 455–463, 2003
    5. E. G. Bremer, J. Schlessinger, and S. Hakomori “Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor” J. Biol. Chem., Vol. 261 pp. 2434–2440, 1986
    6. T. Chung, H. Choi, Y. Lee, and C. Kim “Molecular mechanism for transcriptional activation of ganglioside GM3 synthase and its function in differentiation of HL-60 cells” Glycobiology, Vol. 15:3, pp. 233-244, 2004