N-Dodecanoyl-NBD-lactosylceramide

CATALOG # 1630
Amount 50 µg
Price $295.00
Qty
 
N-Dodecanoyl-NBD-lactosylceramide, fluorescent
  • Catalog #:1630
  • Scientific Name:N-Dodecanoyl-NBD-lactosylceramide
  • Common Name:N-Dodecanoyl-NBD-beta-D-lactosylsphingosine; N-C12:0-NBD-beta-D-Lactosylsphingosine; N-C12:0-NBD-Lactosylceramide
  • Empirical Formula:C48H81N5O16
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:984
  • Unit:50 µg
  • Solvent:none
  • Source:semisynthetic
  • Purity:98+%
  • Analytical Methods:TLC
  • Natural Source:bovine buttermilk
  • Solubility:chloroform/methanol, 2:1
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. Y. Hayashi et al. “A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates” Analytical Biochemistry, Vol. 345(2) pp. 181-186, 2005
    2. Ravinder Pannu et al. “A Novel Role of Lactosylceramide in the Regulation of Tumor Necrosis Factor -mediated Proliferation of Rat Primary Astrocytes: IMPLICATIONS FOR ASTROGLIOSIS FOLLOWING NEUROTRAUMA” Journal of Biological Chemistry, Vol. 280 pp. 13742-13751, 2005
    3. Glyn Dawson “Glycosphingolipid levels in an unusual neurovisceral storage disease characterized by lactosylceramide galactosyl hydrolase deficiency: lactosylceramidosis” Journal of Lipid Research, Vol. 13 pp. 207-219, 1972
    4. NanLing Gong “Lactosylceramide recruits PKC/ and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells” Proceedings of the National Academy of Sciences, Vol. 101:17 pp. 6490-6495, 2004