N-Hexanoyl-NBD-glucosylceramide(1mg)

CATALOG # 1622-001
Amount 1mg
Price $625.00
Qty
 
N-Hexanoyl-NBD-glucosylceramide, fluorescent
  • Catalog #:1622-001
  • Scientific Name:N-Hexanoyl-NBD-glucosylceramide
  • Common Name:N-C6:0-NBD-beta-D-Glucosylsphingosine; N-C6:0-NBD-Glucosylceramide
  • Empirical Formula:C36H59N5O11
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:738
  • Unit:1mg
  • Solvent:none
  • Source:semisynthetic
  • Purity:98+%
  • Analytical Methods:TLC; identity confirmed by MS
  • Natural Source:bovine
  • Solubility:chloroform/methanol, 5:1; methanol
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. J. Kok et al. “Fluorescent, short-chain C6-NBD-sphingomyelin, but not C6-NBD-glucosylceramide, is subject to extensive degradation in the plasma membrane: implications for signal transduction related to cell differentiation” Biochemistry Journal, Vol. 309 pp. 905-912, 1995
    2. Y Liu et al. “Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and -catenin signaling” Molecular Cancer, Vol. 9 pp. 145, 2010
    3. C. Walden et al. “Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of -Glucosidase 2: IMPLICATIONS FOR SPERMATOGENESIS” The Journal of Biological Chemistry, Vol. 282 pp. 32655-32664, 2007
    4. D. Sillence et al. “Glucosylceramide modulates membrane traffic along the endocytic pathway” Journal of Lipid Research, Vol. 43(11) pp. 1837-1845, 2002