N-Tricosanoyl ceramide trihexoside

CATALOG # 1524
Amount 500 µg
Price $425.00
N-Tricosanoyl ceramide trihexoside
  • Catalog #:1524
  • Scientific Name:N-Tricosanoyl ceramide trihexoside
  • Common Name:N-C23:0-Ceramide trihexoside; N-Tricosanoyl globotriaosylceramide
  • Empirical Formula:C59H111NO18
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:1122
  • Unit:500 µg
  • Solvent:none
  • Source:semisynthetic
  • Purity:98+%
  • Analytical Methods:TLC, identity confirmed by MS
  • Natural Source:porcine RBC
  • Solubility:DMSO, hot methanol, chloroform/methanol, 2:1
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:
    1. S. Ashkenazi, and T. Cleary, “Rapid method to detect shiga toxin and shiga-like toxin I based on binding to globotriosyl ceramide (Gb3), their natural receptor.” J Clin Microbiol., Vol. 27:6 pp. 1145-1150, 1989
    2. S. Bekri, et al. "The role of ceramide trihexoside (globotriaosylceramide) in the diagnosis and follow-up of the efficacy of treatment of Fabry disease: a review of the literature" Cardiovasc Hematol Agents Med Chem, Vol. 4:4 pp. 289–297, 2006
    3. J. Groener, et al. “HPLC for simultaneous quantification of total ceramide, glucosylceramide, and ceramide trihexoside concentrations in plasma” Clin Chem., Vol. 53:4 pp. 742-747, 2007
    4. K. Mills, A. Johnson, B. Winchester, “Synthesis of novel internal standards for the quantitative determination of plasma ceramide trihexoside in Fabry disease by tandem mass spectrometry” FEBS Lett., Vol. 27 pp. 171-176, 2002
    5. C. Menge, et al. “Globotriaosylceramide (Gb(3)/CD77) is synthesized and surface expressed by bovine lymphocytes upon activation in vitro” Vet Immunol Immunopathol., Vol. 83 pp.19-36, 2001