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CATALOG # 1790


  • Catalog #:1790
  • Scientific Name:(+)-delta-Tocopherol
  • Common Name:8-Methyltocol
  • Empirical Formula:C27H46O2
  • CAS#:119-13-1
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:403
  • Unit:50 mg/ml, 1 ml
  • Solvent:hexane
  • Source:natural
  • Purity:TLC, 95%; GC, 98%
  • Analytical Methods:TLC,GC, identity confirmed by MS
  • Natural Source:plant
  • Solubility:methanol, ethanol, hexane, chloroform
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:Yes


Application Notes:

delta-Tocopherol is one of the forms of vitamin E and in animal tissues has been found to have much less retention than alpha-tocopherol.1 Due to its having only one methyl group meta to the phenolic hydroxyl group and no ortho-methyl groups, delta-tocopherol has much less antioxidant activity in vivo than alpha-tocopherol which has two ortho-methyl groups and a meta-methyl group. Vitamin E is involved in immune function, cell signaling, regulation of gene expression, and other metabolic processes. Vitamin E also inhibits lipid oxidation by donating its phenolic hydrogen to lipid free radicals.2 Antioxidant activity in vivo is normally alpha>beta>gamma>delta but the antioxidant potency may depend on various chemical and physical situations.3 The ortho-methyl substitution of the chroman head plays a vital role in the antioxidant activity of tocopherols while the phytyl tail is very important for proper positioning in the biomembranes. The antioxidant properties of vitamin E may delay memory loss in Down’s syndrome patients due to their protection from harmful oxidation caused by excess activity of Superoxide dismutase. Vitamin E is only naturally produced in plants, algae, and some cyanobacteria and is therefore an important dietary nutrient for humans and animals.

1. S. Chiku, K. Hamamura and T. Nakamura “Novel urinary metabolite of d-delta-tocopherol in rats” Journal of Lipid Research, Vol. 25 pp. 40-48, 1984
2. G. W. Burton and K. Ingold Autoxidation of biological molecules. 1. Antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro, U. J. Am. Chem. Soc., 103, 6472-6477, 1981
3. Anchalee Sirikhachornkit, Jai W. Shin, Irene Baroli, and Krishna K. Niyogi Replacement of a -tocopherol by ß -tocopherol enhances resistance to photo-oxidative stress in a xanthophyll-deficient strain of Chlamydomonas reinhardtii, Eukaryotic Cell, doi:10.1128, 2009
Price $227.00

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