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3-Hydroxyhexanoic acid

CATALOG # 1747


  • Catalog #:1747
  • Scientific Name:3-Hydroxyhexanoic acid
  • Common Name:3-Hydroxy C6:0 fatty acid
  • Empirical Formula:C6H12O3
  • CAS#:10191-24-9
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:132
  • Unit:25 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC; GC; identity confirmed by MS
  • Solubility:chloroform, ethanol, methanol
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No


Application Notes:

This 3-hydroxyhexanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Short chain-length polyhydroxyalkenoate monomers such as 3-hydroxyhexanoic acid may have pharmaceutical properties. The biologically natural chiral (R)-3-hydroxyhexcanoic acid is an intermediate in fatty acid biosynthesis. 3-hydroxyhexanoic acid has been found in patients with ketoacidosis.1 3- hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxyacyl- CoA dehydrogenases.2,3

1. T. Niwa, K. Yamada, T. Ohki, H. Furukawa “3-Hydroxyhexanoic acid: an abnormal metabolite in urine and serum of diabetic ketoacidotic patients” Journal of Chromatography, vol. 337 pp. 1-7, 1985
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001
Price $149.00

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