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3-Hydroxytetradecanoic acid

CATALOG # 1735


  • Catalog #:1735
  • Scientific Name:3-Hydroxytetradecanoic acid
  • Common Name:3-Hydroxy C14:0 fatty acid
  • Empirical Formula:C14H28O3
  • CAS#:3422-31-9
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:244
  • Unit:25 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC, GC, identity confirmed by MS
  • Melting Point:80-81°C
  • Solubility:chloroform, methanol, ethanol
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No


Application Notes:

This 3-hydroxytetradecanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. 3- Hydroxytetradecanoic acid is used as a biomarker for the molecular subunit endotoxin Lipid-A (where it is the most abundant saturated fatty acid) which is responsible for toxicity.1 Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Medium chain-length polyhydroxyalkenoate monomers such as 3-hydroxytetradecanoic acid may have some pharmaceutical properties. 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3- hydroxy-acyl-CoA dehydrogenases.2,3

1. D. Kirschner, S. Que Hee, and C. Clark “Method for detecting the 3-hydroxymyristic acid component of the endotoxins of gram-negative bacteria in compost samples” Am Ind Hyg Assoc J, vol. 46(12) pp. 741-746, 1985
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3- hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001
Price $227.00

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