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9(Z),11(Z)-Octadecadienoic acid

CATALOG # 1248


  • Catalog #:1248
  • Scientific Name:9(Z),11(Z)-Octadecadienoic acid
  • Common Name:9-cis, 11-cis-CLA
  • Empirical Formula:C18H32O2
  • CAS#:544-70-7
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:280
  • Unit:25 mg
  • Source:synthetic
  • Purity:96+%
  • Analytical Methods:GC; TLC; identity confirmed by MS
  • Melting Point:40-42°C
  • Solubility:ethanol, methanol, chloroform, ethyl ether
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No


Application Notes:

9(Z),11(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Due to its being a minor component it is very helpful as a comparison to the major isomers 9(Z),11(E)-CLA and 10(E),12(Z)-CLA. 9(Z),11(Z)-CLA has been demonstrated to have a more potent antiproliferative effect than the more common 9(Z),11(E)-CLA isomer when incubated with human colon cancer cells.

1. Helen B. MacDonald, Journal of the American College of Nutrition, Vol. 19, No. 90002, 111S-118S, 2000
2. Mairéad Coakley, Mark C. Johnson, Emma McGrath, Shafiqur Rahman, R. Paul Ross, Gerald F. Fitzgerald, Rosaleen Devery, Catherine Stanton, Nutrition and Cancer, 56(1) pp. 95-102, 2006
Price $185.00

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