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Methyl 3-hydroxytridecanoate

CATALOG # 1734


  • Catalog #:1734
  • Scientific Name:Methyl 3-hydroxytridecanoate
  • Common Name:3-Hydroxy C13:0 methyl ester
  • Empirical Formula:C14H28O3
  • CAS#:150024-70-7
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:244
  • Unit:25 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:TLC, GC, identity confirmed by MS
  • Solubility:chloroform; ethyl ether
  • Physical Appearance:solid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No


Application Notes:

This 3-hydroxytridecanoic acid methyl ester is a high purity standard that is ideal for analysis and biological systems. 3- Hydroxytridecanoic acid is unusual in many biological systems and is therefore useful as an internal standard.1 However 3- hydroxytridecanoic acid is a major constituent of some organisms such as in the anaerobic bacterium Veillonella.2 3- Hydroxy fatty acids are intermediates in fatty acid biosynthesis and have been found to be converted to the omega-fatty acid by the enzyme CYP4F11 and then into dicarboxylic acids in vivo.3 3-Hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxy-acyl-CoA dehydrogenases.4 Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms and are used as biodegradable plastics.5 Medium chain-length polyhydroxyalkenoate monomers may have pharmaceutical properties.

1. L Larsson and A. Saraf “Use of gas chromatography-ion trap tandem mass spectrometry for the detection and characterization of microorganisms in complex samples” Molecular Biotechnology, vol. 7 pp. 279-287, 1997
2. D. Bishop et al. “Occurrence of 3-hydroxytridecanoic and 3-hydroxypentadecanoic acids in the lipopolysaccharides of Veillonella” Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol. 231 pp. 274-276, 1971
3. M. Dhar et al. “Omega-oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11” Journal of Lipid Research, vol. 49, pp. 612-624, 2008
4. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001
5. J. Gangoiti et al. “Production of Chiral (R)-3-Hydroxyoctanoic Acid Monomers, Catalyzed by Pseudomonas fluorescens GK13 Poly(3-Hydroxyoctanoic Acid) Depolymerase” Applied and Environmental Microbiology, vol. 76 pp. 3554-3560, 2010
Price $238.00

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